[en] Positron lifetime quantum-mechanical calculations were carried out for investigation of point defects in α-Fe containing hydrogen atoms. The electron wave functions have been obtained in the local density approximation [LDA] to the density functional theory [DFT]. On the bases of calculated results, the behavior of empty nano-voids and nano-voids with hydrogen were discussed. It was found that hydrogen in larger three-dimensional vacancy clusters changes the annihilation characteristics dramatically. The hydrogen atoms are trapped by lattice vacancies. These results provide physical insight for positron interactions with defects in α-Fe and can be used for prediction of hydrogen generation for the design of fusion reactors