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AbstractAbstract
[en] Objective: To observe the effect of laminaria japonica polysaccharides (LJP) on local radiation damage of testis tissue in male rats. Methods: The Wistar rats were randomly divided into 4 groups: the normal group, the model group, positive control group and LJP treatment group (50 mg·kg-1·d-1). LJP was applied to the treatment group for 10 d before local irradiation with γ-ray (6.0 Gy). The morphological change of the testis, organ index of testis and epididymides, sperm count, motility rate, superoxide dismutase (SOD) activity and malonic aldehyde (MDA) contents were measured. Results: LJP could make the damaged testis recover to near normal, elevate the organ index of testis and epididymides, promote the sperm count and motility rate, increase the activity of SOD and decrease the contents of MDA in testis tissue. Conclusions: LJP could inhibit testis tissue damage induced by local radiation, hence enhance the significant radioprotective effect to testis tissue. LJP has the conspicuous protective effect on radiation damage of testis tissue. (authors)
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Source
1 fig., 3 tabs., 12 refs.
Record Type
Journal Article
Journal
Chinese Journal of Radiological Medicine and Protection; ISSN 0254-5098;
; v. 27(6); p. 540-543

Country of publication
ALGAE, ANIMALS, AQUATIC ORGANISMS, BIOLOGICAL EFFECTS, BIOLOGICAL RADIATION EFFECTS, BODY, CARBOHYDRATES, CHROMOPHYCOTA, DISEASES, DRUGS, ELECTROMAGNETIC RADIATION, ENZYMES, GAMETES, GERM CELLS, GONADS, INJURIES, IONIZING RADIATIONS, IRRADIATION, MALE GENITALS, MAMMALS, ORGANIC COMPOUNDS, ORGANS, OXIDOREDUCTASES, PLANTS, PROTEINS, RADIATION EFFECTS, RADIATIONS, RESPONSE MODIFYING FACTORS, RODENTS, SACCHARIDES, SEAWEEDS, VERTEBRATES
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