[en] The Institute of Energetic and Nuclear Research - IPEN is a research and development institution, located in a densely populated area, in the city of Sao Paulo. The nuclear fuel cycle was developed from the Yellow Cake to the enrichment and reconversion at IPEN. After this phase, all the technology was transferred to private enterprises and to the Brazilian Navy (CTM/SP). Some plants of the fuel cycle were at semi-industrial level, with a production over 20 kg/h. As a research institute, IPEN accomplished its function of the fuel cycle, developing and transferring technology. With the necessity of space for the implementation of new projects, the uranium hexafluoride (UF₆) production plant was chosen, since it had been idle for many years and presented potential leaking risks, which could cause environmental aggression and serious accidents. This plant decommission required accurate planning, as this work had not been carried out in Brazil before, for this type of facility, and there were major risks involving gaseous hydrogen fluoride aqueous solution of hydrofluoric acid (HF) both highly corrosive. Evaluations were performed and special equipment was developed, aiming to prevent leaking and avoid accidents. During the decommissioning work, the CNEN safety standards were obeyed for the whole operation. The environmental impact was calculated, showing to be not relevant.The radiation doses, after the work, were within the limits for the public and the area was released for new projects. (author)