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AbstractAbstract
[en] This research thesis deals with the different biological mechanisms, notably the repair and apoptosis mechanisms induced by irradiation in cells. After a presentation of the genotoxic stress and DNA repair mechanisms, the author discusses the cellular response to a DNA double-strand break, and the regulation of these response mechanisms (how a cellular response emerges: life or death). The next part deals with the apoptosis (cell death by necrosis or apoptosis), and presents the BCL-2 protein family. Results are then reported on laboratory studies of the effect of this protein family
Original Title
Controle de la recombinaison homologue par l'oncoproteine anti-apoptotique Bcl-2
Primary Subject
Source
Dec 2003; 227 p; Available from the INIS Liaison Officer for France, see the 'INIS contacts' section of the INIS-NKM website for current contact and E-mail addresses: http://www.iaea.org//inis/Contacts/; Also available from Universite Paris Diderot - Paris 7 - Bibliotheque centrale, Batiment Les Grands Moulins - 59, quai Panhard et Levassor - Case 7051, 75205 CEDEX 13 PARIS (France); These Microbiologie fondamentale
Record Type
Report
Literature Type
Thesis/Dissertation
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INIS VolumeINIS Volume
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