[en] A theoretical study of the nuclear reaction cross sections for proton induced reactions on each of the Cu isotopes ⁶³Cu and ⁶⁵Cu have been performed in the proton energy ranges from some threshold values up to 50 MeV. The produced nuclei were different isotopes of ln, Cu, Ni, Co and Mn, some of which have found important applications. The reaction cross section calculations were performed using the ALlCE-IPPE code which depends on the pre-equilibrium compound nucleus model. This code is suitable for the studied energy and isotopic mass ranges. About 14 excitation functions for the different reactions have been constructed from the calculated cross section values. The excitation function curves for the proton reactions with natural copper targets have been constructed from those for enriched targets using the natural abundances of the copper isotopes. Comparisons between the calculated excitation functions with those previously experimentally measured were given whenever experimental values were available. Some statistical parameters were introduced to control the quality of the fitting between both experimental and theoretical calculated cross section values