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[en] The 64Cu (T1/2 = 12.7 h, β- 37.1%, β+ 17.9%) is suitable radioisotope for use in positron emission tomography, due to its physical properties, which make it ideal for therapy (β-) and for use in diagnosis (β+), e.g. hypoxic tumors. Its production is possible in biomedical cyclotrons (with energy of protons 11-18 MeV). We used a nuclear reaction 64Ni (p, n) for its preparation because it has a large cross section also at the energies of small biomedical cyclotrons. A disadvantage of this reaction is a high price of the target material, eliminated by developing a very simple way of recycling 64Ni. Ion exchange chromatography (adsorbent Bio-Rad AG1-X8) was used for separation of 64Cu from target material. Separation was carried out on the separation module developed by us. Yield of 64Cu for 100 mg 64Ni (99.09%) on the gold target was 104 MBq/μAh. To measure the product activity and to determinate radioisotope contamination were used: ionization chamber (Curiementor), gamma spectrometry (HPGe detector) and liquid scintillation spectrometry (TDCR method). (authors)
Source
Skrabalek, P. (ed.) (Zdruzenie pre regulaciu rizika z radonu, Banska Stiavnica (Slovakia)); Zdruzenie pre regulaciu rizika z radonu, Banska Stiavnica (Slovakia); [127 p.]; ISBN 978-80-971150-3-6; 
; Oct 2012; p. 1-5; 13. Stiavnica Days 2012; XIII. Stiavnicke dni 2012; Banska Stiavnica (Slovakia); 2-4 Oct 2012; PROJECT VMSP-P-0075-09; 5 refs., 1 tab., 4 figs.
; Oct 2012; p. 1-5; 13. Stiavnica Days 2012; XIII. Stiavnicke dni 2012; Banska Stiavnica (Slovakia); 2-4 Oct 2012; PROJECT VMSP-P-0075-09; 5 refs., 1 tab., 4 figs.