[en] GLAST is the new generation of Gamma-ray telescope and should dramatically improve our knowledge of the gamma-ray sky when it is launched on September 7. 2007. Data from the beam test that was held at GANIL with low energy ions were analyzed in order to measure the light quenching factor of CsI for all kinds of ions from proton to krypton of energy between 0 and 73 MeV per nucleon. These results have been very useful to understand the light quenching for relativistic ions that was measured during the GSI beam test. The knowledge of light quenching in GLAST CsI detectors for high energy ions is required for the on-orbit calibration with cosmic rays to succeed. Hadronic background rejection is another major issue for GLAST, thus, all the algorithms rely on the GLAST official Monte-Carlo simulation, GlastRelease. Hadronic cascade data from the GSI beam test and from another beam test held at CERN on the SPS have been used to benchmark hadronic cascade simulation within the framework of GEANT4, on which GlastRelease is based. Testing the good reproduction of simple parameters in GLAST-like calorimeters for hadronic cascades generated by 1.7 GeV, 3.4 GeV, 10 GeV and 20 GeV protons or pions led us to the conclusion that at high energy the default LHEP model is good enough, whereas at low energy the Bertini intra-nuclear cascade model should be used. (author)