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AbstractAbstract
[en] A model of an ultrasound-driven encapsulated microbubble (EMB) oscillation near biomaterial wall is presented and used for describing the microflow-induced shear stress on the wall by means of a numerical method. The characteristic of the model lies in the explicit treatment of different types of wall for the EMB responses. The simulation results show that the radius-time change trends obtained by our model are consistent with the existing models and experimental results. In addition, the effect of the elastic wall on the acoustic EMB response is stronger than that of the rigid wall, and the shear stress on the elastic wall is larger than that of the rigid wall. The closer the EMB to the wall, the greater the shear stress on the wall. The substantial shear stress on the wall surface occurs inside a circular zone with a radius about two-thirds of the bubble radius. This paper may be of interest in the study of potential damage mechanisms to the microvessel for drug and gene delivery due to sonoporation. (paper)
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Source
Available from http://dx.doi.org/10.1088/1674-1056/24/9/094301; Country of input: International Atomic Energy Agency (IAEA)
Record Type
Journal Article
Journal
Chinese Physics. B; ISSN 1674-1056;
; v. 24(9); [6 p.]

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