Results 1 - 1 of 1
Results 1 - 1 of 1. Search took: 0.024 seconds
[en] Radionuclidic purity tests of "1"8F radiopharmaceuticals (Na"1"8F and fluorodeoxyglucose ["1"8F]FDG) and radionuclide composition analysis of irradiated water ["1"8O]H_2O were performed. The measurements were conducted using a High-Purity Germanium (HPGe) detector and a liquid scintillation counter. Radionuclide identification and activity measurements were performed for samples from different stages of the production process. Most of the impurities were detected on QMA (quaternary methylammonium) anion exchange columns and in liquid wastes. Using liquid scintillation counting, the activity of "3H resulting from the "1"8O[p, "3H]"1"6O reaction was determined. It was shown that all of the impurities were efficiently determined and eliminated in the radiopharmaceuticals synthesis process and that the final products meet the requirements set by relevant regulations. - Highlights: • Radionuclidic purity tests of "1"8F radiopharmaceuticals were performed. • Different steps of synthesis process were studied. • Use of gamma spectrometer with HPGe detector revealed many long lived impurities. • "3H activity, from "1"8O[p, "3H]"1"6O, was determined by liquid scintillation counting. • It was proven that all impurities were efficiently eliminated in final product.