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[en] The occurrence of various chemicals in our life creates a need to evaluate whether they pose a threat to human body. There are many methods capable of detecting potential mutagenic or genotoxic effect. The Smart test was chosen to test mutagenic effect of low-temperature plasma, which is nowadays used in medicine, material decontamination and degradation of pharmaceuticals. When a mutational event during larval development occurs, spots on the wings are being formed. The frequency and size of the spots reveals the mutagenic potency of the tested substance. To evaluate the mutagenic effect of low-temperature plasma, larvae were treated with multiple doses. Our results show that plasma did not exhibit any mutagenic effect in all of the tested doses. Next we studied if it could work as an antimutagenic agent. Experiments with plasma along with ethyl methanesulphonate (EMS), a known mutagen, suggest that plasma treatment did reduce the negative effect of EMS, thus this agents could possess antimutagenic effect. (authors)
Source
Galambos, M. (ed.) (Department of Inorganic Chemistry, Faculty of Natural Sciences, Comenius University, Bratislava (Slovakia)); Dzugasova, V. (ed.); Sevcovicova, A. (ed.) (Department of Genetics, Faculty of Natural Sciences, Comenius University, Bratislava (Slovakia)); Bobovska, A. (ed.) (Department of Physical and Theretical Chemistry, Faculty of Natural Sciences, Comenius University, Bratislava (Slovakia)); Faculty of Natural Sciences, Comenius University, Bratislava (Slovakia). Funding organisation: Sponsors: Slovenske jadrove forum, 91700 Trnava (Slovakia); Eppendorf Czech and Slovakia s.r.o., Bratislava (Slovakia); Nadacia Curie, Bratislava (Slovakia); 1554 p; ISBN 978-80-223-4310-7; 
; 3 May 2017; p. 466-471; Student Scientific Conference PriF UK 2017; Studentska vedecka konferencia PriF UK 2017; Bratislava (Slovakia); 26 Apr 2017; GRANT VEGA-1/0904/14; Also available from http://fns.uniba.sk/studium/svk/zborniky-svk/; 4 figs., 14 refs.
; 3 May 2017; p. 466-471; Student Scientific Conference PriF UK 2017; Studentska vedecka konferencia PriF UK 2017; Bratislava (Slovakia); 26 Apr 2017; GRANT VEGA-1/0904/14; Also available from http://fns.uniba.sk/studium/svk/zborniky-svk/; 4 figs., 14 refs.