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AbstractAbstract
[en] The method of stop flow analysis has been used in rabbits together with radioactive sodium and potassium injected in the middle of a six minutes period of arrest of urine flow during an osmotic diuresis. Urine was subsequently collected in 60 ta 80 mg samples. The specific activities of sodium and potassium suggest that both ions pass directly from the renal interstitial tissue into the urine at different and distinct areas in the tubules. The whole distal segment, including the area of active reabsorption of this ion, is impermeable to sodium in the direction interstitial tissue to lumen. The adjacent, more proximal tubule is, however, extremely permeable. The distal tubular impermeability to potassium is more limited. The specific activity already having reached a maximum at the level of active sodium reabsorption. Reprint of a paper published in 'Revue Francaise d'Etudes Cliniques et Biologiques', n. 5, vol IV, p. 471-474
[fr]
La methode de 'diurese interrompue' a ete utilisee chez le lapin, en association avec l'emploi de sodium et de potassium radioactifs (diurese osmotique, indicateurs injectes au milieu d'une interruption de six minutes, urines recueillies ensuite par fractions de 60 a 80 mg). Les courbes de radioactivite specifique indiquent que les ions Na+ et K+ passent directement du milieu interstitiel renal dans l'urine a travers des segments definis et differents du nephron. Pour le sodium, on note une impermeabilite (dans le sens interstice-lumen) de toute la region distale, y compris la zone de reabsorption active. Par contre, le segment adjacent plus proximal apparait hautement permeable. Pour le potassium, l'impermeabilite distale est plus limitee, car sa radioactivite specifique atteint deja un maximum dans la zone de reabsorption active de sodium. Reproduction d'un article publie dans la 'Revue Francaise d'Etudes Cliniques et Biologiques', n. 5, vol IV, p. 471-474Original Title
Etude de la permeabilite des diverses parties du nephron pour les ions sodium et potassium
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Source
1959; 7 p; 8 refs.
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Report
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ALKALI METAL COMPOUNDS, ANIMALS, AZOLES, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BIOLOGICAL MATERIALS, BIOLOGICAL WASTES, BODY, BODY FLUIDS, CHARGED PARTICLES, DIFFUSION, HALIDES, HALOGEN COMPOUNDS, HETEROCYCLIC COMPOUNDS, HOURS LIVING RADIOISOTOPES, IMIDAZOLES, IMINES, INORGANIC PHOSPHORS, INTERMEDIATE MASS NUCLEI, IODIDES, IODINE COMPOUNDS, IONS, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, KINETICS, LIGHT NUCLEI, MAMMALS, MATERIALS, MILLISECONDS LIVING RADIOISOTOPES, NUCLEI, ODD-ODD NUCLEI, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, ORGANS, PHOSPHORS, PHOTOMETRY, PHYSICAL PROPERTIES, POTASSIUM ISOTOPES, RADIOISOTOPES, SODIUM COMPOUNDS, SODIUM HALIDES, SODIUM ISOTOPES, VERTEBRATES, WASTES
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