[en] Highlights: • RGO-Fe₂O₃-MoS₂ was prepared by two-step hydrothermal method. • Heterojunction accelerates the separation of photo-generated carriers. • RGO-Fe₂O₃-MoS₂ displays preferable photocatalytic activity. - Abstract: 3D quasi-hierarchical Z-scheme RGO-Fe₂O₃-MoS₂ nanocomposites were developed as a high performance photocatalyst driven by visible light. The RGO layers help uniformly disperse α-Fe₂O₃ NPs and MoS₂ nanosheets, resulting in large specific surface area of the nanocomposites. Moreover, when involved in photocatalytic process for MB degradation, the RGO layers not only serve as current collector to enhance the photo-generated charge carriers’ transport but also form abundant heterostructures with Fe₂O₃ and MoS₂ to effectively separate the photo-induced electron-hole pairs. The Fe−O−C bonds are formed between Fe₂O₃ and RGO, implying the intimate interface contact which can accelerate the separation of photogenerated carriers. Moreover, the loading of MoS₂ nanosheets, which contributes to large amount of light absorption, is conducive to create a plenty of heterojunctions with Fe₂O₃ and effectively separate photo-induced electron-hole pairs. As a result, the typical Z-scheme RGO-Fe₂O₃-MoS₂ nanocomposites containing 62.1 wt% of α-Fe₂O₃ and 15.2 wt% of MoS₂ show drastically enhanced photocatalytic activity for visible-light-driven MB and RhB degradation compared to the pristine Fe₂O₃ NPs, and together with excellent stability.