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Smolobochkin, Andrey V.; Gazizov, Almir S.; Syakaev, Victor V.; Anikina, Ekaterina A.; Burilov, Alexander R.; Pudovik, Michail A., E-mail: agazizov@iopc.ru2017
AbstractAbstract
[en] Herein we report the synthesis of previously unknown 2-arylpyrrolidine-1-carboxamides containing aminophenol moiety via a novel approach developed by us, namely, acid-catalyzed cyclization of (4,4-diethoxybutyl)ureas in the presence of 3-aminophenol. The proposed approach benefits from mild reaction conditions, use of inexpensive and common solvents and catalyst, and allows to obtain target compounds with good to high yields. Graphical abstract: < Image>.
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Copyright (c) 2017 Springer-Verlag GmbH Austria; Article Copyright (c) 2017 Springer-Verlag Wien
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