[en] Based on a one-dimensional Smoluchowski equation we have developed the theory of concentration nonlinearity of a suspension of transparent microspheres under the action of a gradient force in an interference laser field. The numerical solution of a system of recurrence equations resulting from the Smoluchowski equation after expansion of the microsphere concentration $N(z,t)$ in the harmonic series has allowed us to determine the dependence of the concentration nonlinearity settling time on the intensity of the incident radiation. In the diffusion limit, we have derived the expression for the optical Kerr coefficient, which is found to be $8.5\times <!--\; ??\; -->{10}^{-<!--\; ???\; -->10}{\text{cm}}^2{\text{W}}^{-<!--\; ???\; -->1}$ for an aqueous suspension of latex microspheres with a radius of $1.17\text{μ<!-- ?? -->}\text{m}$ and a concentration of $6.5\times <!--\; ??\; -->{10}^{10}{\text{cm}}^{-<!--\; ???\; -->3}$. Diffraction of a probe wave on a light-induced concentration grating is considered as a method for studying a nonlinear concentration response of an artificial highly efficient nonlinear medium for laser radiation of long pulse duration. (paper)