[en] This work examines the radial evolution of a high burnup fast reactor mixed-oxide (MOX) fuel pellet irradiated at the Fast Flux Test Facility (FFTF) using scanning (SEM) and transmission electron microscopy (TEM). At 21.3% fissions per initial metal atoms (FIMA), the sample analyzed in this work is likely among the highest burnup oxide fuel samples ever evaluated using TEM. Initial SEM examination focused on the characterization of the fuel microstructure and solid fission product behavior as a function of radial position. The fuel pellet underwent extensive restructuring as demonstrated by columnar grain formation near the central void. Oxide fission product phases were confined to near the fuel centerline and decomposed from perovskite BaZrO₃ to the fluorite ZrO₂ type crystal structure. Metallic five metal precipitates (FMPs) were observed at all radial positions and the Pd-rich metallic phase increased in area fraction moving toward the pellet surface. TEM examination focused on the determination of dislocation density ranging from the fuel pellet center to the pellet surface. Dislocation density was highest in the cooler regions of the fuel pellet, with the outer edge experiencing grain refinement and high defect concentrations consistent with the rim structure. The results of the paper highlight the variable dislocation behavior as a function of radial position in high burnup MOX fuels, as well as describe the largely unexplored change in crystal structure of the oxide solid fission product phase.