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Kanno, I.; Nishimatsu, D.; Funama, F., E-mail: kanno@nucleng.kyoto-u.ac.jp2019
AbstractAbstract
[en] Boron neutron caputure therapy (BNCT) is a promising treatment for invasive tumors. The BNCT utilizes the energy deposition by alpha particle and 7Li created by the neutron capture reaction of 10B. One of the problem of BNCT is the imaging of 10B distribution during the treatment. The gamma rays with the energy of 0.478 MeV emitted by 7Li can be exploited for this purpose. The photon counting of the gamma rays, however, is very difficult due to the high gamma ray background caused by 2.22 MeV gamma rays originated by the neutron reactions with 1H. To overcome this difficulty, the authors propose a method to measure gamma rays as electric current by a "transXend" detector, which had been invented by them for energy-resolved X-ray computed tomography. In this paper, the feasibility study on 10B distribution imaging in a water phantom with a tumor region is shown by simulation studies. For establishing the relationship between electric currents induced in the transXend detector by gamma rays and 10B concentration, the attenuation of gamma rays by the phantom should be taken into account. For this purpose, a neural network was employed. The results showed good agreement with the training data used for the neural network.
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Source
Available from http://dx.doi.org/10.1088/1748-0221/14/02/C02002; Country of input: International Atomic Energy Agency (IAEA)
Record Type
Journal Article
Journal
Journal of Instrumentation; ISSN 1748-0221;
; v. 14(02); p. C02002

Country of publication
ALPHA PARTICLES, BORON, BORON 10, CONCENTRATION RATIO, ELECTRIC CURRENTS, EMISSION, ENERGY ABSORPTION, ENERGY LOSSES, GAMMA RADIATION, HYDROGEN 1, LITHIUM 7, NEOPLASMS, NEURAL NETWORKS, NEUTRON CAPTURE THERAPY, NEUTRONS, PHANTOMS, PHOTON COUNTING, SIMULATION, SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY, X RADIATION
ABSORPTION, BARYONS, BORON ISOTOPES, CHARGED PARTICLES, COMPUTERIZED TOMOGRAPHY, CURRENTS, DIAGNOSTIC TECHNIQUES, DIMENSIONLESS NUMBERS, DISEASES, ELECTROMAGNETIC RADIATION, ELEMENTARY PARTICLES, ELEMENTS, EMISSION COMPUTED TOMOGRAPHY, FERMIONS, HADRONS, HYDROGEN ISOTOPES, IONIZING RADIATIONS, ISOTOPES, LIGHT NUCLEI, LITHIUM ISOTOPES, LOSSES, MEDICINE, MOCKUP, NEUTRON THERAPY, NUCLEAR MEDICINE, NUCLEI, NUCLEONS, ODD-EVEN NUCLEI, ODD-ODD NUCLEI, RADIATIONS, RADIOLOGY, RADIOTHERAPY, SEMIMETALS, SORPTION, STABLE ISOTOPES, STRUCTURAL MODELS, THERAPY, TOMOGRAPHY
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