[en] In this research, the molecule N'-((E)-5-methoxy-2-((1-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4,5-dihydro-1H-1,2,3-triazol-4-yl)methoxy) benzylidene)-4- methyl-1,2,3-thiadiazole-5-carbohydrazide were synthesized and characterized by several conventional analysis methods. Its physical properties and thermal stability was studied. The synthesis was conducted based on D-glucose using concept of click chemistry reaction mechanism. Some of the reaction was conducted using microwave irradiation. The synthesis steps initiated by adding propargyl bromide to 2-hydroxy-5-methoxy benzaldehyde under vigorous measure of moister isolated environment to produce propargyl ether(5-methoxy-2-(prop-2-yn-1-yloxy)benzaldehyde) 3 in which has terminal triple bond. In parallel a glycocyl azide was prepared by applying glycocyl acetate (acetate for protection) via bromination and then substituted by treatment with sodium azide to produce glycocyl azide in which actively reacted with terminated triple bond by click reaction in the present of Cu(II) catalyst. The coupling reaction of terminal alkyle group in compound 3 with azide group of (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6- azidotetrahydro-2H-pyran-3,4,5-triyl triacetate) has given high yield of triazole. The produced triazole molecule is triazole(2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(4-((2-formyl-4-methoxy)methyl)-1H-1,2,3- triazole-1-yl)tetrahydro-2H-pyran-3,4,5,-triyacetate) 7 undergoes further reaction to substitute carbonyl of the aromatic with hydrazide by applying 4-methyl-1,2,3-thiadiazole-5-carbohydrazide reagent. The glycocyl acetate was de-esterifide by sodium methoxide to remove the acetate protection. The structure of all these synthesized molecules was confirmed by FTIR, H1NMR, C13NMR. (author)