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[en] In this report for accreditation to supervise research (HDR), the author first gives an overview of her research activities within the DAM (Directorate of Military Applications) which addressed the cooling of cryogenic targets and the study of solid reactivity and long term behaviour (L1H hydrolysis, vacuum degassing of materials, and within the DEN (Directorate of Nuclear Energy). Then, she focuses on more recent researches within the DEN which addressed hydrogen production (introduction to two-phase flows) and chemistry-transport couplings in extraction devices, and also the study of flows in liquid-liquid extraction columns, and the development of a modelling of precipitation in emulsion.