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[en] After having indicated some highlights for the considered period, this activity report presents the various research activities of the laboratory which address the main following issues: fundamental masses and interactions (research in particle physics), the matter-antimatter asymmetry, the study of black matter and of cosmic radiation, cosmology and black energy. Then, after a presentation of activities related to academic teaching and research-based training, it presents the various skills and technical realisations (activities of various departments, development and upgrades of instruments and experiments). The organisation and operation of the laboratory are then described, and actions related to the scientific and communication animation are indicated (participation to seminars and other events).