[en] Presently, a brain-inspired neuromorphic system has attracted a great deal of attention. Moreover, global synaptic modulation functions mimicked on a single solid-state device are interesting for a brain-inspired neuromorphic platform. Here, solid-state bio-polymer electrolyte gated oxide neuron transistors with multi-gates are fabricated. The device demonstrates crucial synaptic mechanisms including experience-dependent plasticity and heterosynaptic plasticity. Most importantly, global modulatory heterosynaptic mechanisms with dynamical reconfiguration of excitatory and inhibitory synaptic behaviors are demonstrated. Moreover, modulation between excitatory integration and inhibitory integration is realized. Interestingly, the proposed oxide neuron transistors can compile a post-synaptic current response in the binary code of ASCII, indicating potential applications in human–machine interfaces. The proposed neuromorphic device provides a new, simple, and versatile building block for a brain-inspired multifunctional neuromorphic platform. (paper)