Filters
Results 1 - 1 of 1
Results 1 - 1 of 1.
Search took: 0.017 seconds
AbstractAbstract
[en] Objective: To assess the efficacy of diffusion-weighted MR imaging (DWI) for evaluating testicular spermatogenic function. Methods: 18 men (mean age: 28.1 ± 3.7 years, range: 20-40 years) with testicular spermatogenesis hypofunction confirmed by percutaneous testes biopsy, volunteers with normal semen analysis including 18 young men (mean age: 25.4 ± 3.1 years, range: 20-30 years), 22 middle-aged men (mean age: 35.4 ± 3.3 years, range: 31-40 years), and 16 older men (mean age: 43.4 ± 4.3 years, range: 41-50 years) were included in the study. All subjects underwent conventional 3 T MRI and DWI using EPI sequence with b values of 0, 900, and 4000 s/mm2. The ADC values were measured by placing the largest possible regions of interest on the testes without including necrosis and testicular edge on the automatically generated ADC maps. Testicular ADC values in each group were compared and the optimal cutoff value for diagnosing testicular spermatogenesis hypofunction was determined using ROC curve analysis. Results: Average testicular ADC value in group A, group B, group C and group D were (0.479 ± 0.025), (0.446 ± 0.018), (0.458 ± 0.033), and (0.468 ± 0.033) mm2/s, respectively. The average ADC values of the three control groups were significantly different (P<0.001) and increased with age from (0.446±0.018) mm2/s in young, (0.458 ± 0.033) mm2/s in middle-aged, to (0.468 ± 0.033) mm2/s in older men. The average ADC values of patients with testicular spermatogenesis hypofunction (0.479 ± 0.025) mm2/s were significantly higher than those in each control group (P < 0.001). The optimal cutoff value of testicular ADC value for diagnosing testicular spermatogenesis hypofunction by ROC analysis was 0.473 mm2/s with 84.1% sensitivity and 73.7% specificity. Conclusion: The testicular ADC values are useful for differentiating testicular spermatogenesis hypofunction from normal. (authors)
Primary Subject
Source
2 figs., 20 refs.; http://dx.doi.org/10.3969/j.issn.1005-8001.2017.01.003
Record Type
Journal Article
Journal
Journal of Diagnostic Imaging and Interventional Radiology; ISSN 1005-8001;
; v. 26(1); p. 15-19

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue