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AbstractAbstract
[en] On the basis of the melanin-specific properties of chloroquine, an 125I-labeled chloroquine analog (NM-113) was synthesized for use in the diagnosis of ocular and dermal melanomas. The limitations and indications for the use of NM-113 in the diagnosis of dermal melanomas are summarized, and its efficiency in the diagnosis of ocular melanomas is discussed. The low probability of side effects (radiation effects) on the retina from a diagnostic dose of 2 m Ci (46 rads) is mentioned. (U.S.)
Original Title
125I
Primary Subject
Source
Croll, M.N. (ed.); p. 161-170; 1974; John Wiley and Sons; New York; Symposium on new techniques in tumor localization and radioimmunoassay; Philadelphia, Pennsylvania, USA; 3 May 1973
Record Type
Book
Literature Type
Conference
Country of publication
AZINES, BETA DECAY RADIOISOTOPES, BIOLOGICAL EFFECTS, BODY, COUNTING TECHNIQUES, DAYS LIVING RADIOISOTOPES, DIAGNOSTIC TECHNIQUES, DISEASES, ELECTRON CAPTURE RADIOISOTOPES, HETEROCYCLIC COMPOUNDS, INTERMEDIATE MASS NUCLEI, IODINE ISOTOPES, ISOTOPES, MEDICINE, NEOPLASMS, NUCLEAR MEDICINE, NUCLEI, ODD-EVEN NUCLEI, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, ORGANS, PYRIDINES, RADIATION EFFECTS, RADIOACTIVE MATERIALS, RADIOISOTOPE SCANNING, RADIOISOTOPES, SENSE ORGANS
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue