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AbstractAbstract
[en] The 125I-fibrinogen uptake test (FUT) was evaluated in a series of 42 subjects to determine its ability to detect active venous thrombosis. Included were patients with recent active thrombosis, patients with long-standing quiescent venous obstruction, and normal controls. In serial tests, increasing isotope uptake was found to occur only in patients with active thrombophlebitis (P less than .01). Consequently, this criterion can serve as an index of active thrombophlebitis. Five patients with known calf vein thrombosis had increasing FUT results at the upper thigh. Phlebography or technetium scans confirmed propagation of the thrombosis. These results suggest a screening value for the FUT in suspected propagating thrombosis. If results are confirmed by subsequent phlebography, major therapeutic changes such as intensification of anticoagulation or venous interruptions can hopefully be made before potentially lethal pulmonary embolism occurs. (U.S.)
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Record Type
Journal Article
Journal
Archives of Surgery (Chicago); v. 109(1); p. 48-51
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BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BLOOD COAGULATION FACTORS, BLOOD VESSELS, CARDIOVASCULAR DISEASES, CARDIOVASCULAR SYSTEM, COUNTING TECHNIQUES, DAYS LIVING RADIOISOTOPES, DISEASES, ELECTRON CAPTURE RADIOISOTOPES, GLOBULINS, HOURS LIVING RADIOISOTOPES, INTERMEDIATE MASS NUCLEI, IODINE ISOTOPES, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, MEDICINE, NUCLEAR MEDICINE, NUCLEI, ODD-EVEN NUCLEI, ORGANIC COMPOUNDS, PROTEINS, RADIOACTIVE MATERIALS, RADIOISOTOPE SCANNING, RADIOISOTOPES, TECHNETIUM ISOTOPES, YEARS LIVING RADIOISOTOPES
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