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AbstractAbstract
[en] Opposition to accelerated nuclear power development is based largely on concern that the potential health hazards of transuranium elements are excessive and that current health protection standards are inadequate. Because no cancer ascribable to plutonium has occurred to date in occupationally exposed populations, an attempt to estimate carcinogenicity in experimental animals has been initiated. Plutonium-bearing ceramic microspheres have been administered by both intravenous and endotracheal routes, and polonium-210 sols have been insufflated for the purpose of comparing localized ''hot particles'' and diffuse irradiation on lifetime tumor incidence. Additional studies involve life shortening, measurement of delayed radiation injury, and histopathological and chromosomal damage as criteria for assessing the hazards of various conditions of radiation exposure. The retention patterns for specific radionuclides in several species are now being extended to include other potential environmental toxic agents
Original Title
Hazards of Pu, 210Po, x radiation, 75Se, 60Co, 113Sn, and 109Cd
Primary Subject
Secondary Subject
Source
Petersen, D.F.; Sullivan, E.M. (comps.); Los Alamos Scientific Lab., N.Mex. (USA); p. 1-14; Apr 1976
Record Type
Report
Literature Type
Progress Report
Report Number
Country of publication
BIOLOGICAL RADIATION EFFECTS, CADMIUM 109, CARCINOGENESIS, CHROMOSOMAL ABERRATIONS, COBALT 60, HAMSTERS, HEALTH HAZARDS, HUMAN POPULATIONS, INTERNAL CONVERSION RADIOISOTO, INTRAVENOUS INJECTION, LIFE SPAN, LUNGS, METABOLISM, MICE, MICROSPHERES, PLUTONIUM, POLONIUM 210, RETENTION, SELENIUM 75, SURVIVAL TIME, TIN 113, TRANSURANIUM ELEMENTS, X RADIATION
ACTINIDES, ALPHA DECAY RADIOISOTOPES, ANIMALS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BIOLOGICAL EFFECTS, BODY, CADMIUM ISOTOPES, COBALT ISOTOPES, DAYS LIVING RADIOISOTOPES, ELECTROMAGNETIC RADIATION, ELECTRON CAPTURE RADIOISOTOPES, ELEMENTS, EVEN-EVEN NUCLEI, EVEN-ODD NUCLEI, HAZARDS, HEAVY NUCLEI, INJECTION, INTAKE, INTERMEDIATE MASS NUCLEI, IONIZING RADIATIONS, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, MAMMALS, METALS, MINUTES LIVING RADIOISOTOPES, MUTATIONS, NUCLEI, ODD-ODD NUCLEI, ORGANS, PATHOGENESIS, POLONIUM ISOTOPES, POPULATIONS, RADIATION EFFECTS, RADIATIONS, RADIOISOTOPES, RESPIRATORY SYSTEM, RODENTS, SELENIUM ISOTOPES, TIN ISOTOPES, VERTEBRATES, YEARS LIVING RADIOISOTOPES
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