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Rahn, R.O.; Stafford, R.S.; Hadden, C.T.
Oak Ridge National Lab., Tenn. (USA)1978
Oak Ridge National Lab., Tenn. (USA)1978
AbstractAbstract
[en] The quantum yields for the photolysis of iodinated derivatives of cytosine (leading to the loss of iodine) has been measured for 313 nm radiation and found to decrease from 0.024 for IodCMP down to 0.007 for both Poly(C) and DNA containing 5-IodCyt. In DNA, approximately 1 clean chain break and 1 alkali-labile bond were formed for every 10 iodines lost. Incorporation of iodinated cytosine or uracil into the DNA of Escherichia coli or Bacillus subtilis was shown to have a large effect on the biological survival following 313 nm radiation
Original Title
Escherichia coli, Bacillus subtilis
Primary Subject
Secondary Subject
Source
1978; 5 p; Symposium on DNA repair mechanisms; Keystone, CO, USA; 19 - 24 Feb 1978; Available from NTIS., PC A02/MF A01
Record Type
Report
Literature Type
Conference
Report Number
Country of publication
AMINES, ANTIMETABOLITES, ANTIMITOTIC DRUGS, AZINES, BACILLUS, BACTERIA, BIOLOGICAL EFFECTS, CHEMICAL REACTIONS, CHEMISTRY, DECOMPOSITION, DRUGS, HETEROCYCLIC COMPOUNDS, HYDROXY COMPOUNDS, KINETICS, MICROORGANISMS, NUCLEIC ACIDS, ORGANIC COMPOUNDS, ORGANIC HALOGEN COMPOUNDS, ORGANIC IODINE COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, ORGANIC OXYGEN COMPOUNDS, PYRIMIDINES, RADIATION EFFECTS, REACTION KINETICS, URACILS
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