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[en] This study was conducted to evaluate the possible subacute toxicity of gamma-irradiated Tarakjuk. Tarakjuk was irradiated at a dose of 30 kGy at room temperature. For the animal study, AIN-93G as a control diet and 30 kGy irradiated and non-irradiated Tarakjuk diets were administered to male and female ICR mice (10 mice per group) for 3 months. During the experimental period, the group fed 30 kGy irradiated Tarakjuk did not show any changes in appearance, behavior, mortality, body weight, organ weight, or food consumption compared to control. Further, all biochemical parameters were in normal ranges. In the histopathological examination of liver and kidney tissues of ICR mice, there were no significant differences between the control and 30 kGy irradiated Tarakjuk groups. These results indicate that Tarakjuk irradiated at 30 kGy did not cause any toxic effects under these experimental conditions
[en] Graphical abstract: - Highlights: • LiNi1/3Co1/3Mn1/3O2 was firstly used as a coating layer for LiNi0.8Co0.1Mn0.1O2. • The coating layer is electrochemical active for insertion/de-insertion of lithium ions. • In the co-precipitation process, the coating materials mostly grew on the surface of the host material rather than nucleate alone in the solution. • The coated samples showed good cycling performance and rate capability. - Abstract: A modified LiNi1/3Co1/3Mn1/3O2-coating process is introduced to improve the electrochemical performance of LiNi0.8Co0.1Mn0.1O2 (LNCM811). The coating process is carried on a precursor, Ni0.8Co0.1Mn0.1(OH)2 (NCM811), rather than on LNCM811. Unlike the electro-inert metal oxide coatings, the LiNi1/3Co1/3Mn1/3O2 (LNCM111) layer is electrochemically active and able to relieve reactions between the highly delithiated Li1−μNi0.8Co0.1Mn0.1O2 and the electrolyte on account of the decrease of nickel content in outer layer. The LNCM111-coated LNCM811 material shows superior electrochemical performance, with an initial discharge capacity of 153 mAh g−1 and capacity retention of 90% after 100 cycles at 2C rate between 2.8 and 4.3 V at 60 °C
[en] Amplitude variations with offset or incident angle (AVO/AVA) inversion are typically combined with statistical methods, such as Bayesian inference or deterministic inversion. We propose a joint elastic inversion method in the time and frequency domain based on Bayesian inversion theory to improve the resolution of the estimated P- and S-wave velocities and density. We initially construct the objective function using Bayesian inference by combining seismic data in the time and frequency domain. We use Cauchy and Gaussian probability distribution density functions to obtain the prior information for the model parameters and the likelihood function, respectively. We estimate the elastic parameters by solving the initial objective function with added model constraints to improve the inversion robustness. The results of the synthetic data suggest that the frequency spectra of the estimated parameters are wider than those obtained with conventional elastic inversion in the time domain. In addition, the proposed inversion approach offers stronger antinoising compared to the inversion approach in the frequency domain. Furthermore, results from synthetic examples with added Gaussian noise demonstrate the robustness of the proposed approach. From the real data, we infer that more model parameter details can be reproduced with the proposed joint elastic inversion.
[en] We discovered a new tumor marker MA153 which has been identified as Mu-GlcNAc (Mucin1-N-acetyl-Glucosamine). It can react with monoclonal antibody and a related Aptamer to form the Ma695-Mu-GlcNAc-MA153-A sandwich assay. Taking 1 U/mL as cutoff value, the clinical serum detection results indicated that the tumor specificity of Mu-GlcNAc was 95%, the tumor detection sensitivities were 80%, 74%, 68%, 70%, 75%, 50%, 60%, 55%, 70%, 64%, and 60% for breast cancer, pancreatic cancer, liver cancer, lung cancer, esophagus cancer, mouth cancer, colon cancer, bile duct cancer, ovarian cancer, cervix cancer and uterus cancer, respectively. It is concluded that Mu-GlcNAc is a new multi-tumor tumor marker. (authors)
[en] Seismic inversion performed in the time or frequency domain cannot always recover the long-wavelength background of subsurface parameters due to the lack of low-frequency seismic records. Since the low-frequency response becomes much richer in the Laplace mixed domains, one novel Bayesian impedance inversion approach in the complex Laplace mixed domains is established in this study to solve the model dependency problem. The derivation of a Laplace mixed-domain formula of the Robinson convolution is the first step in our work. With this formula, the Laplace seismic spectrum, the wavelet spectrum and time-domain reflectivity are joined together. Next, to improve inversion stability, the object inversion function accompanied by the initial constraint of the linear increment model is launched under a Bayesian framework. The likelihood function and prior probability distribution can be combined together by Bayesian formula to calculate the posterior probability distribution of subsurface parameters. By achieving the optimal solution corresponding to maximum posterior probability distribution, the low-frequency background of subsurface parameters can be obtained successfully. Then, with the regularization constraint of estimated low frequency in the Laplace mixed domains, multi-scale Bayesian inversion in the pure frequency domain is exploited to obtain the absolute model parameters. The effectiveness, anti-noise capability and lateral continuity of Laplace mixed-domain inversion are illustrated by synthetic tests. Furthermore, one field case in the east of China is discussed carefully with different input frequency components and different inversion algorithms. This provides adequate proof to illustrate the reliability improvement in low-frequency estimation and resolution enhancement of subsurface parameters, in comparison with conventional Bayesian inversion in the frequency domain.
[en] Amplitude variation with offset (AVO) inversion is widely utilized in exploration geophysics, especially for reservoir prediction and fluid identification. Inverse operator estimation in the trust region algorithm is applied for solving AVO inversion problems in which optimization and inversion directly are integrated. The L1 norm constraint is considered on the basis of reasonable initial model in order to improve effciency and stability during the AVO inversion process. In this study, high-order Zoeppritz approximation is utilized to establish the inversion objective function in which variation of with time is taken into consideration. A model test indicates that the algorithm has a relatively higher stability and accuracy than the damp least-squares algorithm. Seismic data inversion is feasible and inversion values of three parameters () maintain good consistency with logging curves. (paper)
[en] A Babinet-inverted optical nanoantenna analogue of electromagnetically induced transparency based on the coupling between two magnetic dipole antennas and a magnetic octupole antenna in a Au film waveguide is demonstrated. Simulation results indicate that a pronounced elimination occurs in the radiating spectrum due to the coupling-induced radiation suppression. A two-oscillator electromagnetically induced transparency model is used to describe the antenna. The coupling coefficient between the magnetic dipole antennas and the magnetic octupole antenna is calculated using the model and is found to decline exponentially with the increase of the distance between them. Such an antenna can be directly integrated with optical waveguides or transmission lines, thus is of fundamental significance for the applications in nano-optics, such as the optical device miniaturizations and photonic circuit integrations. (paper)
[en] We introduce a new consensus pattern, named a successive lag cluster consensus (SLCC), which is a generalized pattern of successive lag consensus (SLC). By applying delay-dependent impulsive control, the SLCC of first-order and second-order multi-agent systems is discussed. Furthermore, based on graph theory and stability theory, some sufficient conditions for the stability of SLCC on multi-agent systems are obtained. Finally, several numerical examples are given to verify the correctness of our theoretical results. (paper)
PurposeThe demand for titanium dental implants has risen sharply. However, the clinical success rate of implant surgery needs to be improved. In this paper, we report a novel surface modification strategy, large-grit sandblasting combined with micro-arc oxidation (SL-MAO), aiming to promote peri-implant bone formation and osseointegration of titanium implants.
Materials and methodsModified titanium samples were prepared by large-grit sandblasting and acid etching (SLA), micro-arc oxidation (MAO), and SL-MAO. The resulting topographical changes and chemical composition of the samples were examined by scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS), respectively, and the biocompatibility and bioactivity were analyzed by bone-marrow mesenchymal stem cells (BMMSC) adhesion tests. Modified titanium implants were also inserted into the femurs of beagle dogs, and their competence of osseointegration was appraised by quantitative histomorphometry and micro-computed-tomography (micro-CT) analyses.
ResultsCompared to SLA and MAO techniques, SL-MAO surface modification further enhanced titanium surfaces by creating a topographic morphology characterized by both micron-sized craters and sub-micron-scale pits, and resulted in superior chemical composition, which promoted cell adhesion, proliferation, and osteogenic differentiation. SL-MAO-modified titanium implants osseointegrated more efficiently than SLA or MAO controls, with significantly higher bone-area (BA) ratio and bone-implant contact (BIC) in the peri-implant region.
ConclusionsThe SL-MAO surface modification technique optimized the surface properties of titanium implants and enhanced peri-implant bone formation and osseointegration.
[en] The transmissions of oxygen ions through Al2O3 nanocapillaries each 50 nm in diameter and 10 μm in length at a series of different tilt angles are measured, where the ions with energies ranging from 10 to 60 keV and charge states from 1 up to 6 are involved. The angular distribution and the transmission yields of transported ions are investigated. Our results indicate both the existence of a guiding effect when ions pass through the capillary and a significant dependence of the ion transmission on the energy and the charge state of the ions. The guiding effects are observed to be enhanced at lower projectile energies and higher charge states. Meanwhile, the results also exhibit that the transmission yields increase as the tilt angle decreases at a given energy and charge state. (atomic and molecular physics)