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AbstractAbstract
[en] The various role of the formation of HDBP and H2MBP in γ irradiated 30% TBP-Kerosene-1 mol/L HNO3 mixed phase (with a phase ratio of 0/A = 1: 1) is studied. A comparative result in irradiated 30% TBP-Kerosene single organic phase has been made. It shows that in irradiated mixed phase, the major source of HDBP formation is the organic phase and the H2MBP concentration yielded in irradiated mixed phase is 30%-40% higher than that in irradiated single phase. In addition, the HDBP G value in irradiated mixed phase is much high than that in irradiated single phase during the absorbed dose <2 x 105 Gy, but when the absorbed dose >2 x 105 Gy. there is no remarkable difference for it. The reason of the difference for the radiolysis of TBP in irradiated mixed phase and single phase has been discussed, the existence of much more O2 and H2O in irradiated mixed phase system plays a main role
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Journal Article
Journal
Journal of Radiation Research and Radiation Processing; ISSN 1000-3436;
; CODEN FYYXEA; v. 10(1); p. 1-6

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ALKALI METAL COMPOUNDS, BUTYL PHOSPHATES, CARBON COMPOUNDS, CHEMICAL RADIATION EFFECTS, CHEMICAL REACTIONS, DECOMPOSITION, ELECTROMAGNETIC RADIATION, ENERGY SOURCES, ESTERS, FOSSIL FUELS, FUELS, GAS OILS, HYDROGEN COMPOUNDS, INORGANIC ACIDS, INORGANIC COMPOUNDS, IONIZING RADIATIONS, LIQUID FUELS, NITROGEN COMPOUNDS, ORGANIC COMPOUNDS, ORGANIC PHOSPHORUS COMPOUNDS, OXYGEN COMPOUNDS, PETROLEUM, PETROLEUM DISTILLATES, PETROLEUM FRACTIONS, PETROLEUM PRODUCTS, PHOSPHORIC ACID ESTERS, RADIATION EFFECTS, RADIATIONS, REPROCESSING, SEPARATION PROCESSES, SULFUR COMPOUNDS
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AbstractAbstract
[en] The effects of BSO, a potent radiosensitizing and chemical sensitizing chemical, on the incidence of micronuclei in four different cell lines have been studied using the cytokinesis-block (CB) method. The number of micronuclei in cultured human peripheral lymphocytes, Chinese hamster cells and human breast cancer cells were not affected by 0.1-2 mmol/L BSO treatment alone. However, significant increase in the incidence of micronuclei in these cells could be detected when BSO was used in combination with γ-irradiation. Linear relationship between the incidence of micronuclei and the radiation dose was observed
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Journal Article
Journal
Journal of Radiation Research and Radiation Processing; ISSN 1000-3436;
; CODEN FYYXEA; v. 10(1); p. 51-53

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AbstractAbstract
[en] Using the differential pulse polarography, the values of the half wave potential (E1/2) of the new radiosensitizer CM, Misonidazole MISO and Metronidazole were measured, and also compared under the same condition. The results showed that the magnitude of the E1/2 was as follows: MISO>CM>Metronidazole. The data demonstrates that their reduction ability correlates well with their radiosensitization. Although the electron affinity potency of CM and its radiosensitization in vitro are in the middle, CM has properties of tumor-affinity to a certain extent, low toxicity and high therapeutic index, and the preliminary clinical results indicate that CM is a low toxic and efficient radiosensitizer
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Journal Article
Journal
Journal of Radiation Research and Radiation Processing; ISSN 1000-3436;
; CODEN FYYXEA; v. 10(2); p. 113-116

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AbstractAbstract
[en] The male and female mice were irradiated with different doses (from 0 to 200 cGy) of 60Co gamma ray, their splenic antibody forming cells were measured with the Plaque Forming Cell (PFC) technique. The results show that the PFCs of both the male and female mice were depressed and the depression was of dose-depending. When the dose was 200 cGy, about 85% of the PFCs were inhabited. No difference in the radiosensitivity between the male and female mice was found
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Journal Article
Journal
Journal of Radiation Research and Radiation Processing; ISSN 1000-3436;
; CODEN FYYXEA; v. 10(1); p. 54-56

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AbstractAbstract
[en] The radiation polymerization technique was used for immobilization testosterone propionate into crosslinked network of poly hydroxyethyl methacrylate to prepare slowly released male sex hormone drug which is used for testicular prosthesis. The testicular prosthesis was transplanted into the scrotum of male rabbit whose testes was excised 2 months before the transplantation. Then the level of male sex hormone in serum was measured by radioimmunoassay once a week after transplantation. The results of measurement in a period of 6 months were shown that the testicular prosthesis has a stable release of male sex hormone. The testosterone level in serum of the castrated male rabbits rises markedly and finally stabilizes at the level of 429 ± 36 ng/100 ml after transplantation. Macroscopic examination of biopsies taken from the tissues around the testicular prosthesis showed that tissue compatibility was revealed well
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Journal Article
Journal
Journal of Radiation Research and Radiation Processing; ISSN 1000-3436;
; CODEN FYYXEA; v. 10(2); p. 65-69

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ANDROGENS, ANDROSTANES, BODY, CARBOXYLIC ACIDS, CHEMICAL REACTIONS, DIAGNOSTIC TECHNIQUES, GONADS, HORMONES, HYDROXY COMPOUNDS, ISOTOPE APPLICATIONS, KETONES, MALE GENITALS, MONOCARBOXYLIC ACIDS, ORGANIC ACIDS, ORGANIC COMPOUNDS, ORGANS, RADIATION EFFECTS, RADIOASSAY, STEROID HORMONES, STEROIDS, TRACER TECHNIQUES
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AbstractAbstract
[en] The effects of electron beam irradiation on polyethylene foam of open cell type have been studied. Experiments for determining of gel fraction and physical-mechanical properties of irradiated polyethylene foam of open cell type as a function of dose, respectively, were carried out. The dimensional stability of irradiated specimens at elevated temperatures was measured. It was found that tensile strength did not change and gel fraction increased when the specimen was irradiated in nitrogen atmosphere with increasing dose up to 300 kGy. The result shows that dimensional stability of polyethylene foam of open cell type after being kept in an oven at 70 deg C and 110 deg C for 22 h is improved by irradiation in nitrogen atmosphere. The similar results of irradiated EVA foam of open cell type irradiated foam of open cell type were obtained
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Record Type
Journal Article
Journal
Journal of Radiation Research and Radiation Processing; ISSN 1000-3436;
; CODEN FYYXEA; v. 9(4); p. 246-251

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AbstractAbstract
[en] The effects of a new radiosensitizing compound-metronidazolamic acid (CM) and its Ca+2 chelation compound (CMCa) on the DNase activity of mouse hepatic tumor (H22) cells were observed. The effects of CM, CMCa or Ca+2 at same molarity and their combination with γ-rays irradiation on DNase activity of H22 cells were also observed respectively. The results showed that CM could activate the DNase activity to be increased as CM concentration increased below 5 mmol/L. The highest DNase activity was activated by CM at 5 mmol/L. The degree of activation between CM and CMCa had no significant different (p > 0.05), whereas free Ca+2 alone had no effect. The activation of combined CM or CMCa and radiation groups were greater than that of each given independently they possessed a coordinate activation. However free Ca+2 still could not activate the DNase activity after γ-irradiation. From all the above results, it is suggested that CM or CMCa improved the tumor radiotherapeutic efficiency probable due to its activation the DNase activity of cancer cells which enhanced the DNA damage. It might be one of the radiosensitizing mechanism in tumor radiotherapy
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Record Type
Journal Article
Journal
Journal of Radiation Research and Radiation Processing; ISSN 1000-3436;
; CODEN FYYXEA; v. 9(2); p. 65-68

Country of publication
ALCOHOLS, ALKALINE EARTH METAL COMPOUNDS, ANIMALS, ANTINEOPLASTIC DRUGS, AZOLES, CARCINOMAS, DISEASES, DRUGS, ELECTROMAGNETIC RADIATION, ENZYMES, ESTERASES, HETEROCYCLIC COMPOUNDS, HYDROLASES, HYDROXY COMPOUNDS, IMIDAZOLES, IONIZING RADIATIONS, MAMMALS, MEDICINE, NEOPLASMS, NITRO COMPOUNDS, NUCLEASES, NUCLEIC ACIDS, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, PHOSPHODIESTERASES, PROTEINS, RADIATIONS, RESPONSE MODIFYING FACTORS, RODENTS, THERAPY, VERTEBRATES
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AbstractAbstract
[en] The polysaccharide from spirulina platensis (PSP) was further purified by sephadex G-100. PSP contained about 77.63% of sugar. The effect of PSP on immunological function of irradiated mice were studied. The results showed that PSP significantly improved organ weight, lymphocyte number and lymphocyte transformation in spleen of mice irradiated by 5 Gy
Primary Subject
Record Type
Journal Article
Journal
Journal of Radiation Research and Radiation Processing; ISSN 1000-3436;
; CODEN FYYXEA; v. 15(3); p. 186-188

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ANIMAL CELLS, ANIMALS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BIOLOGICAL EFFECTS, BIOLOGICAL MATERIALS, BLOOD, BLOOD CELLS, BODY FLUIDS, CARBOHYDRATES, COBALT ISOTOPES, CONNECTIVE TISSUE CELLS, DRUGS, ELECTROMAGNETIC RADIATION, INTERMEDIATE MASS NUCLEI, INTERNAL CONVERSION RADIOISOTOPES, IONIZING RADIATIONS, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LEUKOCYTES, MAMMALS, MATERIALS, MINUTES LIVING RADIOISOTOPES, NUCLEI, ODD-ODD NUCLEI, ORGANIC COMPOUNDS, PLANTS, RADIATION EFFECTS, RADIATIONS, RADIOISOTOPES, RESPONSE MODIFYING FACTORS, RODENTS, SOMATIC CELLS, VERTEBRATES, YEARS LIVING RADIOISOTOPES
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AbstractAbstract
[en] Character change of operational amplifiers was compared in X- and γ-radiation environments. Dose enhancement effect of X- and γ-radiation was studied to operational amplifiers. Relative dose enhancement factors (RDEF) measured are about 3.4∼12.4 in the experiment. SiO2/Si interface trapped hole charges and interface states are main failure model of operational amplifiers in X- and γ- radiation environments
Record Type
Journal Article
Journal
Journal of Radiation Research and Radiation Processing; ISSN 1000-3436;
; CODEN FYYXEA; v. 15(2); p. 80-85

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AbstractAbstract
[en] Effects of O2 and dose rate on the radiolysis of rabbit hepatic metallothionein-I(MT-I) in phosphate buffer solution at pH 8.0 have been studied. Active species (OH and H2O2) formed under irradiation principally attack the Zn-S bonds in the β-domain of MT-I and as a result, give birth to disulfide bonds, and the formation of disulfide bonds mainly occurs intra-molecularly. The radiolysis of N2- or N2O-saturated MT-I solutions resulted in sulfhydryl-group-decrease with G-SH- = 4.2 and 7.2 respectively, whereas G values of dimer (G(MT-I)2) were only 0.32 and 0.67. A short chain-reaction exists in the decrease of sulfhydryl groups when O2-saturated MT-I was irradiated, but it contributed little to G(MT-I)2. However, the damaged MT-I can be repaired completely by reduced glutathione. The reaction between H2O2 and MT-I also was investigated, and k2 = 10 mol· dm-3s·-1 for RS-(MT-I) + H2O2 → RSOH + OH- was obtained. Furthermore, the radiolysis mechanism of MT-I was discussed on the basis of above mentioned results and good material balances were achieved
Record Type
Journal Article
Journal
Journal of Radiation Research and Radiation Processing; ISSN 1000-3436;
; CODEN FYYXEA; v. 12(4); p. 193-198

Country of publication
ANIMALS, BODY, CHARGED PARTICLES, CHEMICAL RADIATION EFFECTS, CHEMICAL REACTIONS, DECOMPOSITION, DIGESTIVE SYSTEM, DRUGS, ELECTROMAGNETIC RADIATION, GLANDS, IONIZING RADIATIONS, MAMMALS, METALLOPROTEINS, ORGANIC COMPOUNDS, ORGANS, PEPTIDES, POLYPEPTIDES, PROTEINS, RADIATION EFFECTS, RADIATIONS, RADIOPROTECTIVE SUBSTANCES, RESPONSE MODIFYING FACTORS, VERTEBRATES
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