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Srdoc, D.; Breyer, B.
Proceedings of the first symposium on neutron dosimetry in biology and medicine1972
Proceedings of the first symposium on neutron dosimetry in biology and medicine1972
AbstractAbstract
No abstract available
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Burger, G.; Schraube, H. (Gesellschaft fuer Strahlen- und Umweltforschung m.b.H., Neuherberg/Munich (F.R. Germany). Inst. fuer Strahlenschutz) (eds.); Ebert, H.G. (ed.) (Commission of the European Communities, Brussels (Belgium). Industrial, Technological and Scientific Affairs); Commission of the European Communities, Luxembourg. Center for Information and Documentation; v. 1 p. 149-157; Sep 1972; First symposium on neutron dosimetry in biology and medicine; Neuherberg/Munich, F.R. Germany; 15 May 1972; 2 figs.
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Buhl, S.N.
Tennessee Univ., Oak Ridge (USA). School of Biomedical Sciences; Oak Ridge National Lab., Tenn. (USA)1972
Tennessee Univ., Oak Ridge (USA). School of Biomedical Sciences; Oak Ridge National Lab., Tenn. (USA)1972
AbstractAbstract
No abstract available
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1972; 30 p; 12. international symposium on basic biology; Cali, Colombia; 27 Nov 1972
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No abstract available
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Columbia Univ., New York (USA). Radiological Research Lab; p. 225-303; 1 Jul 1972
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Evans, H.H.
Case Western Reserve Univ., Cleveland, OH (United States). Dept. of Radiology. Funding organisation: USDOE Office of Energy Research, Washington, DC (United States)1997
Case Western Reserve Univ., Cleveland, OH (United States). Dept. of Radiology. Funding organisation: USDOE Office of Energy Research, Washington, DC (United States)1997
AbstractAbstract
[en] The objective of this research was to investigate the dose-response relationship with regard to the lethal and mutagenic effects of exposure of cells to radon and its decay products. Dose-rate dependence was studied, as well as the nature of the DNA lesions. The effect of DNA repair on the lethal and mutagenic effects of exposure and on the character of the DNA lesions was investigated by comparing the response of L5178Y strains that differ in their ability to rejoin X radiation-induced DNA double strand breaks. The nature of radon/radon daughter-induced mutational lesions in human lymphoblasts was also investigated
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1997; 17 p; CONTRACT FG02-88ER60658; Also available from OSTI as DE97006788; NTIS; US Govt. Printing Office Dep
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Report
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Progress Report
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Mullenders, L.H.F.; Hoffen, A. van; Oosterwijk, M. van; Vrieling, H.; Natarajan, A.T.; Zeeland, A.A. van
Abstracts of the Conference on Mechanisms of DNA Repair and Mutagenesis on the 100. Anniversary of the Discovery of Polonium and Radium1997
Abstracts of the Conference on Mechanisms of DNA Repair and Mutagenesis on the 100. Anniversary of the Discovery of Polonium and Radium1997
AbstractAbstract
No abstract available
Original Title
after UV irradiation
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Source
111 p; ISBN 83-906782-6-8;
; 1997; p. 32; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw (PL); Warsaw (Poland); Mechanisms of DNA Repair and Mutagenesis on the 100. Anniversary of the Discovery of Polonium and Radium; Warsaw (Poland); 8-11 Oct 1997

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Miscellaneous
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Wojewodzka, M.; Kruszewski, M.; Iwanenko, T.; Collins, A.R.
Abstracts of the Conference on Mechanisms of DNA Repair and Mutagenesis on the 100. Anniversary of the Discovery of Polonium and Radium1997
Abstracts of the Conference on Mechanisms of DNA Repair and Mutagenesis on the 100. Anniversary of the Discovery of Polonium and Radium1997
AbstractAbstract
No abstract available
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Source
111 p; ISBN 83-906782-6-8;
; 1997; p. 87; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw (PL); Warsaw (Poland); Mechanisms of DNA Repair and Mutagenesis on the 100. Anniversary of the Discovery of Polonium and Radium; Warsaw (Poland); 8-11 Oct 1997

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Miscellaneous
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Petcu, I.; Savu, D.; Moisoi, N.; Koeteles, G.J.
Low doses of ionizing radiation: Biological effects and regulatory control. Contributed papers1997
Low doses of ionizing radiation: Biological effects and regulatory control. Contributed papers1997
AbstractAbstract
[en] The experiment performed in vitro intended to examine whether an adaptive response could be elicited on lymphocytes by low-level contamination of whole blood with tritiated water and if the modification of the dose rate has any influence on it. Lymphocytes pre-exposed to 3HOH (0.2 - 6.6 MBq/ml) and subsequently irradiated with I Gy γ-rays showed micronuclei frequency significantly lower (40% - 45%) than the expected member (sum of the yields induced by 3HOH and γ-rays separately). The degree of the radioresistance induced by HTO pre-treatments became higher with decreasing dose-rate for a rather similar total adapting dose. In vivo, the aim of the study was to investigate if different dose rates are inducing modulation of the lipid peroxidation level and of the thymidine uptake in different tissues of animals contaminated by HTO ingestion. The total doses varied between 5 and 20 cGy and were delivered as chronic (100 days) or acute contamination (5 days). It was observed that only doses about 20 cGy caused a dose-rate dependent increase of the lipid peroxidation level in the tissues of small intestine, kidney and spleen. Both chronic and acute contamination did produce reduced incorporation of thymidine in the cells of bone marrow. The most effective decrease of thymidine uptake was induced by the acute contamination in the lower dose domain (approx. 5 cGy). Our hypothesis is that in this dose domain the modification of thymidine uptake could be due to changes at the level of membrane transport. (author)
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International Atomic Energy Agency, Vienna (Austria); World Health Organization, Geneva (Switzerland); United Nations Scientific Committee on the Effects of Atomic Radiation, Vienna (Austria); 696 p; ISSN 1011-4289;
; Nov 1997; p. 312-315; International conference on low doses of ionizing radiation: Biological effects and regulatory control; Seville (Spain); 17-21 Nov 1997; IAEA-CN--67/95; 10 refs, 1 fig., 2 tabs.

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ANIMAL CELLS, AZINES, BIOLOGICAL EFFECTS, BIOLOGICAL MATERIALS, BLOOD, BLOOD CELLS, BODY FLUIDS, CHALCOGENIDES, CHEMICAL REACTIONS, CONNECTIVE TISSUE CELLS, HETEROCYCLIC COMPOUNDS, HYDROGEN COMPOUNDS, IRRADIATION, LEUKOCYTES, MATERIALS, NUCLEOSIDES, NUCLEOTIDES, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, OXIDES, OXYGEN COMPOUNDS, PYRIMIDINES, RADIATION EFFECTS, RIBOSIDES, SOMATIC CELLS, TRITIUM COMPOUNDS, WATER
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Distel, L.; Distel, B.; Roessner, B.; Schwotzer, G.; Sauer, R.; Eyrich, W.; Fritsch, M.; Teufel, A.; Besserer, J.; Boer, J. de; Moosburger, M.; Quicken, P.
6. Workshop on heavy-charged particles in biology and medicine. Book of abstracts1997
6. Workshop on heavy-charged particles in biology and medicine. Book of abstracts1997
AbstractAbstract
[en] At the tandem accelerator laboratories in Munich and Erlangen vertical beamlines were installed last year. The advantage of a vertical beamline is that cells can be irradiated in a medium at 37 C and with simultaneous gassing, therefore also in physiological conditions. First experiments were carried out at the accelerator in Munich with a proton energy of 25 MeV. Chinese Hamster cells B14 were irradiated in Petri dishes where the base was of 1 mm polystyrol or 2 μm hostaphan foils. The cell survival was measured by the cell survival assay and the repopulation of the colonies by the total colony volume. A solution of DNA with protein was irradiated to study DNA double strand breaks by constant field gel electrophoresis and DNA protein crosslinks by the nitrocellulose filter assay. For cell survival, total colony volume and DNA double-strand breaks X-rays and protons gave corresponding results, while with protons, higher yields of DNA-protein crosslinks were observed than with X-rays. (orig.)
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Kraft, G.; Langbein, K. (eds.); Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany); 290 p; Sep 1997; p. D5.1-D5.4; 6. Workshop on heavy-charged particles in biology and medicine; Baveno (Italy); 29 Sep - 1 Oct 1997
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ACCELERATORS, BEAMS, BIOLOGICAL EFFECTS, CHEMICAL REACTIONS, DISEASES, DISPERSIONS, DNA DAMAGES, ELECTROMAGNETIC RADIATION, ELECTROSTATIC ACCELERATORS, HOMOGENEOUS MIXTURES, INJURIES, IONIZING RADIATIONS, IRRADIATION, MIXTURES, NUCLEIC ACIDS, NUCLEON BEAMS, ORGANIC COMPOUNDS, PARTICLE BEAMS, POLYMERIZATION, RADIATION EFFECTS, RADIATIONS
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Durante, M.; Gialanella, G.; Grossi, G.; Pugliese, M.; Cella, L.; Greco, O.; George, K.; Yang, T.C.
6. Workshop on heavy-charged particles in biology and medicine. Book of abstracts1997
6. Workshop on heavy-charged particles in biology and medicine. Book of abstracts1997
AbstractAbstract
[en] We have investigated the effectiveness of heavy ions in the induction of chromosomal aberrations in mammalian cells by the recent technique of fluorescence in situ hybridization (FISH) with whole-chromosome probes. FISH-painting was used both in metaphase and interphase (prematurely condensed) chromosomes. The purpose of our experiments was to address the following problems: (a) the ratio of different types of aberrations as a function of radiation quality (search for biomarkers); (b) the ratio between aberrations scored in interphase and metaphase as a function of radiation quality (role of apoptosis); (c) differences between cytogenetic effects produced by different ions at the same LET (role of track structure). (orig./MG)
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Source
Kraft, G.; Langbein, K. (eds.); Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany); 290 p; Sep 1997; p. C2.1-C2.4; 6. Workshop on heavy-charged particles in biology and medicine; Baveno (Italy); 29 Sep - 1 Oct 1997
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ANIMALS, BARYONS, BEAMS, BIOLOGICAL EFFECTS, BIOLOGICAL RADIATION EFFECTS, CATIONS, CHARGED PARTICLES, ELECTROMAGNETIC RADIATION, ELEMENTARY PARTICLES, ENERGY TRANSFER, FERMIONS, GENETIC EFFECTS, HADRONS, HYDROGEN IONS, HYDROGEN IONS 1 PLUS, IONIZING RADIATIONS, IONS, IRRADIATION, MUTATIONS, NUCLEONS, RADIATION EFFECTS, RADIATIONS, VERTEBRATES
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AbstractAbstract
[en] From several studies of hyperthermia there have been reports that hypoxic cells are more sensitive to heat than their oxic counterparts. Experimental techniques in this investigation eliminated the effect of pH, trypsinization and cell attachment, when assaying the effect of hyperthermia on cells. Under hypoxic conditions, HeLa S3 and Chinese hamster cell-lines did not have an increased sensitivity to heat compared with oxic cells. HeLa S3 cells were protected against heat by hypoxia. Light-microscopy indicated the rupture of the plasma membrane, occasional nuclear budding, membrane vesicles and granulation of cell contents after heating at 430C for 3 hours. Scanning electron micrographs showed that cells were more rounded after heat treatment and that there was an accompanying decrease in the number of microvilli, suggesting that the mechanism of cell attachment was affected. Heated cells should be delicately handled and subjected to the minimal trauma so that an accurate comparison of survival can be made. (author)
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Journal Article
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International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine; ISSN 0020-7616;
; v. 33(1); p. 57-67

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