[en] Calculations of the thermal distribution resulting from the heated discharge water of the nuclear power plant KKU (1300 MW/sub e/) into the Weser River are described. Extensive field-measurements were carried out to provide the necessary data for calibration and verification of the model. Since the Weser is a tidal river the assumption of an infinite receiving body of water as a sink for the dilution of the discharge water is not valid. Hence, a sufficient quantity of new dilution water (that is, water not influenced by previous discharges) is not always supplied to the inshore region, where the plant is sited. However, the determination of a background temperature (i.e. estimation) of the ambient water is not necessary because the model equations are derived from the conservational principles of mass, momentum, and energy for a turbulent, incompressible fluid. The equations are mean-time averaged and depth-averaged and upon being integrated are solved numerically. For the simulation of the thermal plume the module HETRAN (heat transfer program) of UTRANS (unified transport system) is used. The model accurately describes the complex shoreline geometry which is an important factor for plume dispersion, in particular for plumes of large longitudinal extension (up to 40 km) and small plume width

[en] The gamma camera is used to determine the distribution of radio-pharmaceutical preparations in the body (tomography). It has a plate collimator where each gap has a detector from the scintillation plate or photoelement assigned to it. The form of the detectors is matched to the size of gap. The resolution of the gamma camera is improved by the constructional integration of the collimator with the radiation converter parts, because an optimum mutual alignment is guaranteed. (DG)

[en] A method is presented for locating protein antigenic determinants by analyzing amino acid sequences in order to find the point of greatest local hydrophilicity. This is accomplished by assigning each amino acid a numerical value (hydrophilicity value) and then repetitively averaging these values along the peptide chain. The point of highest local average hydrophilicity is invariably located in, or immediately adjacent to, an antigenic determinant. It was found that the prediction success rate depended on averaging group length, with hexapeptide averages yielding optimal results. The method was developed using 12 proteins for which extensive immunochemical analysis has been carried out and subsequently was used to predict antigenic determinants for the following proteins: hepatitis B surface antigen, influenza hemagglutinis, fowl plague virus hemagglutinin, human histocompatibility antigen HLA-B7, human interferons, Escherichia coli and cholera enterotoxins, ragweed allergens Ra3 and Ra5, and streptococcal M protein. The hepatitis B surface antigen sequence was synthesized by chemical means and was shown to have antigenic activity by radioimmunoassay

[en] A ⁴⁰Ca(p',2p) experiment was performed at the TRIUMF facility using a 200 MeV polarized proton beam. Data were acquired at eleven independent pairs of angles for separation energies from 0 to 100 MeV over a wide range of recoil momenta. For eight angle pairs, cross sections and analysing powers were extracted from the data as a function of the energy difference of the final state protons for knockout from the valence states 1d_3/2, 2s_1/2, and 1d_5/2. Cross section and analysing power information was obtained for 3 other angle pairs for only the 2s_1/2 state. The results were compared with Distorted Wave Impulse Approximation (DWIA) calculations which incorporated bound state wave functions, an optical model potential with spin-orbit terms, and a half- off-shell prescription for the free p-p scattering matrix element

[en] Published in summary form only

[en] Published in summary form only

[en] Published in summary form only

[en] BALB/c 3T3 cells were transformed by Kirsten sarcoma virus, and five clones were isolated in soft agar. Average replicon sizes of the transformed cell lines were stimated by the method of fiber-autoradiography and found to be the same size as the nontransformed 3T3 cells, analyzed in parallel. The results indicate that, unlike simian virus 40 and Epstein-Barr virus, Kirsten sarcoma virus does not activate new initiation points for cellular deoxyribonucleic acid replication in murine sarcome virus-transformed BALB/c 3T3 cells

[en] Replicon size was estimated in two Epstein-Barr virus (EBV)-negative human lymphoma lines, BJAB and Ramos, and four EBV-positive lines derived from the former ones by infection (conversion) with two viral strains, B95-8 and P3HR-1. Logarithmic cultures were pulse-labeled with [/sup -3/H]thymidine, and the deoxyribonucleic acid was spread on microscopic slides and autoradiographed by the method of Huberman and Riggs. Three of the four EBV-converted cell lines, BJAB/B95-8, Ra/B95-8, and Ra/HRIK, were found to have significantly shorter replicons (41, 21, 54% shorter, respectively), i.e., more initiation points, than their EBV-negative parents. BJAB/HRIK had replicons which were only slightly shorter (11%) than those of BJAB. However, analysis of track length demonstrated that extensive track fusion occurred during the labeling of BJAB/HRIK, implying that its true average replicon size is shorter than the observed value. The results indicate that in analogy to simian virus 40, EBV activates new initiation points for cellular DNA replication in EBV-transformed cells

[en] Nuclear quadrupole resonance (NQR) spectroscopy has been used to demonstrate the difference in the chemical environment of the ³⁵Cl atoms in a number of chlorinated organic compounds with emphasis on chlorinated pesticides. Assignment of signals to specific chlorine atoms has been made utilizing spectra-structure correlation charts and other available data. Some of the problems arising in the interpretation of the NQR spectral lines are discussed. (author)