Published April 1982 | Version v1
Journal article Metadata-only

Effect of some hemostatics in whole-body irradiated rats

Creators

  • 1. Karlova Univ., Prague (Czechoslovakia). Biofyzikalni Ustav
  • 2. Ustredni Vojenska Nemocnice, Prague (Czechoslovakia)

Description

On the 12th day following whole-body 60Co irradiation of rats with a dose of 8.0 Gy the effect of twelve hemostatic preparations was tested: Hespidon (FRG), Intensian (FRG), Emex (Italy), Adrenoxyl (FRG), Clauden (FRG), Tachostyptan (FRG), Tachostyptan E (FRG), POR 8 (Switzerland), Glypresin (CSSR), Styptanon (Holland), Doxium (Switzerland) and Hemostipticum Revici (FRG). Of the 12 tested commercially produced hemostatic drugs after i. v. administration on the 12th day after whole-body irradiation of rats with 8.0 Gy, the Cliffton method showed a favourable effect on the post-irradiation disorder of hemostasis of Hespidon, Intensian, Doxium and Hemostipticum Revici. (author)

Part of:
Toxicity and effect of flavellagic acid on blood coagulation and hemostasis in healthy whole-body irradiated rabbits

Additional details

Additional titles

Original title (Czech)
Ucinek nekterych hemostatik u celotelove ozarenych krys

Publishing Information

Journal Title
Sb. Lek.
Journal Volume
84
Journal Issue
4
Series
Sb. Lek.
Journal Page Range
122-127
ISSN
0036-5327

INIS

Country of Publication
Czech Republic
Country of Input or Organization
Serbia and Montenegro
INIS RN
13707836
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BLOOD FLOW; GAMMA RADIATION; HEMORRHAGE; POST-IRRADIATION THERAPY; RADIATION SYNDROME; RADIOPROTECTIVE SUBSTANCES; RATS; WHOLE-BODY IRRADIATION
Descriptors DEC
ANIMALS; DISEASES; DRUGS; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; MEDICINE; PATHOLOGICAL CHANGES; RADIATIONS; RESPONSE MODIFYING FACTORS; RODENTS; SYMPTOMS; THERAPY; VERTEBRATES

Optional Information