Published January 1991
| Version v1
Journal article
Polyploidization of rat hepatocytes due to cell fusion under the effect of radiation of different LET
- 1. AN SSSR, Leningrad (USSR). Inst. Yadernoj Fiziki
Description
The method of flow cytometry was used to study polyploidization of hepatocytes following X-, γ-, and neutron-irradiation. Ionizing radiation was shown to induce cell polyploidization by two different ways: (1) cells and nuclei fusion, and (2) restriction of mitosis after DNA replication. RBE of 14 MeV neutrons with respect to fusion was about 5x103. With neutron irradiation, the sensitivity of cells by fusion was not lower than that by chromosome mutations. (author). 6 refs., 6 figs
Additional details
Publishing Information
- Journal Title
- Aalam Al-Zarra
- Journal Issue
- no.13
- Series
- Aalam Al-Zarra.
- CODEN
- AAALE
INIS
- Country of Publication
- Syrian Arab Republic
- Country of Input or Organization
- Syrian Arab Republic
- INIS RN
- 22072497
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Translation
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; CELL CULTURES; CHROMOSOMAL ABERRATIONS; LET; LIVER CELLS; POLYPLOIDY; RATS; RBE
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BIOLOGICAL EFFECTS; ENERGY TRANSFER; MAMMALS; MUTATIONS; PLOIDY; RADIATION EFFECTS; RODENTS; SOMATIC CELLS; VERTEBRATES
Optional Information
- Notes
- Translated from Radiobiologiya (Jan - Feb 1988). v.28(1) p.68-73.