Published January 1988
| Version v1
Journal article
Polyploidization of rat hepatocytes due to cell fusion under the effect of radiation of different let
- 1. AN SSSR, Leningrad. Inst. Yadernoj Fiziki
Description
The method of flow cytometry was used to study polyploidization of hepatocytes following X-, γ-, and neutron-irradiation. Ionizing radiation was shown to induce cell polyploidization by two different ways: (1) cells and nuclei fusion, and (2) restriction of mitosis after DNA replication. RBE of 14 MeV neutrons with respect to fusion was about 5x103. With neutron irradiation, the densitivity of cells by fusion was not lower than that by chromosome mutations
Additional details
Additional titles
- Original title (Russian)
- Poliploidizatsiya gepatotsitov krys, obuslovlennaya sliyaniem kletok pri dejstvii izluchenij s raznoj LPEh
Publishing Information
- Journal Title
- Radiobiologiya
- Journal Volume
- 28
- Journal Issue
- 1
- Series
- Radiobiologiya.
- Journal Page Range
- 68-73
- ISSN
- 0033-8192
- CODEN
- RADOA
INIS
- Country of Publication
- Russian Federation
- Country of Input or Organization
- USSR
- INIS RN
- 19072131
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Is Lead record
- Yes
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; DNA; DOSE-RESPONSE RELATIONSHIPS; GAMMA RADIATION; LET; LIVER CELLS; NEUTRONS; POLYPLOIDY; RATS; RBE; X RADIATION
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BARYONS; BIOLOGICAL EFFECTS; ELECTROMAGNETIC RADIATION; ELEMENTARY PARTICLES; ENERGY TRANSFER; FERMIONS; HADRONS; IONIZING RADIATIONS; MAMMALS; NUCLEIC ACIDS; NUCLEONS; ORGANIC COMPOUNDS; PLOIDY; RADIATION EFFECTS; RADIATIONS; RODENTS; SOMATIC CELLS; VERTEBRATES