Published February 1994
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Technetium and rhenium complexes derived from spiperone. Pt. 3
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Description
The first Re-coordinate compound is at present ready for use in biological screening. The structure of this complex shows similarity to the dopamine D2 receptor binding ligand spiperone. In the preliminary experiments it shall be tested whether this substance has an influence on the uptake of [3H]-spiperone into rat brain sections. The precursors have also been investigated in comparison with the test substance to recognize possible effects caused by the partial structures of the molecule. (orig./EF)
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Additional details
Additional titles
- Subtitle (English)
- Biological evaluation of a 4-fluorobutyrophenone-containing neutral rhenium complex
Publishing Information
- Imprint Title
- Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 1993
- Imprint Pagination
- 171 p.
- Journal Page Range
- p. 43-48.
- Report number
- FZR--32
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 25054511
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- AUTORADIOGRAPHY; BIOLOGICAL MARKERS; BRAIN; DIAGNOSIS; LIQUID SCINTILLATION DETECTORS; NUCLEAR MEDICINE; RADIOACTIVITY; RATS; RHENIUM COMPLEXES; SPIPERONE; STANDARDS; TRITIUM COMPOUNDS
- Descriptors DEC
- ANIMALS; AUTONOMIC NERVOUS SYSTEM AGENTS; BODY; CENTRAL NERVOUS SYSTEM; COMPLEXES; DRUGS; HYDROGEN COMPOUNDS; MAMMALS; MEASURING INSTRUMENTS; MEDICINE; NERVOUS SYSTEM; ORGANS; RADIATION DETECTORS; RODENTS; SCINTILLATION COUNTERS; TRANSITION ELEMENT COMPLEXES; VERTEBRATES