Published 1985 | Version v1
Journal article Metadata-only

Contribution to some radiobiological aspects of the investigation of chemical radiosensitizers. 2

Creators

  • 1. Karlova Univ., Hradec Kralove (Czechoslovakia). Lekarska Fakulta

Description

Total radiation protection against lethal effects of whole-body 60Co γ-irradiation expressed by dose reduction factor (DRF) and dependent on the degree of abdominal compression during irradiation inducing hypoxia in the lower part of the body was studied in rats. Under conditions of gradually ischemia the pO2 in hind leg muscle was measured and the dependence of radiation protection was determined in relation to the medium pO2 values of the muscle. Total radiation protection was reached in maximum ischemia with a DRF value of 2.06

Part of:
Contribution to some radiobiological aspects of the investigation of chemical radiosensitizers of hypoxic cells. 1

Additional details

Additional titles

Subtitle (English)
Protective action of the induced hypoxia of bone marrow against the lethal effect of acute whole-body irradiation in rats

Publishing Information

Journal Title
Radiobiol. Radiother.
Journal Volume
26
Journal Issue
3
Series
Radiobiol. Radiother.
Journal Page Range
325-330
ISSN
0033-8184

INIS

Country of Publication
Germany
Country of Input or Organization
German Democratic Republic
INIS RN
16057684
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Is Lead record
Yes
Descriptors DEI
ABDOMEN; ANOXIA; BONE MARROW; COBALT 60; COMPRESSION; EFFICIENCY; GAMMA RADIATION; ISCHEMIA; LETHAL RADIATION DOSE; MUSCLES; RADIATION PROTECTION; RADIOPROTECTIVE SUBSTANCES; RADIOSENSITIVITY; RATS; RESPONSE MODIFYING FACTORS; WHOLE-BODY IRRADIATION
Descriptors DEC
ANEMIAS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; BODY AREAS; CARDIOVASCULAR DISEASES; COBALT ISOTOPES; DISEASES; DRUGS; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; HEMATOPOIETIC SYSTEM; HEMIC DISEASES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIATION DOSES; RADIATIONS; RADIOISOTOPES; RODENTS; SYMPTOMS; TISSUES; VERTEBRATES; YEARS LIVING RADIOISOTOPES

Optional Information